Services

Your success is our commitment.

Our passion for science is your advantage.

Development of Biologically Active Compounds

Targeted Protein Degradation and Induced Proximity

· PROTAC and molecular glue design· E3 ligase selection strategy· Linker optimization (Linkerology)· E3 ligase ligand development and validation· bRo5 optimisationLEARN MORE

Medicinal Chemistry

· Target druggability assessment· Hit identification and hit-to-lead· Lead optimisation and SAR· Compound design and synthesis· Small molecule drug discovery strategy
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Chemical Probes, Tracers and tool compounds

· Fit-for-purpose probes for new targets· Selectivity profiling and negative controls· Tracers and tags for assay development

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AI Drug Discovery Support and Data Curation

· Domain knowledge· Hands-on experience and understanding· Data filtering and curation for training of AI and machine learning models· Understanding the science behind the dataLEARN MORE

Scientific Due Diligence

· Independent technical assessment of small-molecule deals, for VCs and investors· A clear view on the scientific strength of the asset· The key scientific and execution risks· Reality check on the proposed timeline, milestones, and budget· Targeted questions for the next management call· Broad small-molecule expertise across multiple target classes· Particular depth in induced-proximity modalities, protein kinases and chemical probesLEARN MORE

Custom Synthesis

· Custom synthesis of small molecules· Synthetic route design & scouting· Troubleshooting and optimization of synthetic transformations
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Life Science Project Management

· IBM professional PM certificate· Domain knowledge and experience· Coordination across internal and external partners· Scientific insight and proactive problem solving· Liaising with the network of experts and CROs

How We Operate

First we arrange a free and confidential conversation to learn about your project, goals and challenges and to find out if we are the right fit for each other. Then we will propose how we can contribute, provide high level roadmap, transparent pricing and you will decide if you want to move forward. No obligation, no pressure.

Once we agree on our collaboration, we will develop a detailed plan for your specific situation. Respecting your budget, timelines and requirements, we strive to achieve the most efficient solution.
Depending on your needs, we will perform feasibility analysis, literature review, technical analysis and deliver know-how. If necessary, we will bring the right partners to complement our in house expertise and liaise with CROs or external experts.

If your project requires more than consulting, we will coordinate experimental and laboratory work and activities across all partners. We will continuously monitor progress and proactively resolve problems. We will keep you informed so you will have control over each important step and decision, including unexpected challenges in order to pivot on time if necessary.

At the end we deliver all target compounds, procedures, protocols, biological data or any other valuable results in a suitable format. We will pay attention to data interpretation and knowledge transfer so you leave with understanding, and clear answers, not just data.

Would you like to discuss how we can support your project?

Or would you like to become part of our scientific network as external partner?

Get in touch and explore if we are a good fit for each other